Fig. 1
From: Drug synergy scoring using minimal dose response matrices
Overview of experiment to evaluate minimal dose–response matrices. Chemotherapeutics cytarabine (ara-C) and ribonucleotide reductase inhibitors (RNRi) hydroxyurea (HU) or gemcitabine (dF-dC) are first evaluated in monotherapy dose–response curve (DRC) analyses before being combined in different dose–response (DR) matrix sizes. Following incubation with cells, response to drug treatment is assessed before DR analysis and synergy scoring